博士
助理研究员
邮箱：aliasxia@ucas.ac.cn
教育经历：
2013-09至2019-12，华中科技大学，生命科学院生化与分子系，博士，导师：刘剑峰
2011-09至2013-06，华中科技大学，生命科学院生物物理系，硕士，导师：贺熹
2007-09至2011-06, 山西大学, 生命科学院, 学士
科研与学术工作经历：
2015-03至2017-12，威斯尼斯人wns888入口中国，上海营养所，联合培养，导师：刘勇
2020-06至2022-06，威斯尼斯人wns888入口中国，生物化学与分子卓越创新研究中心，博士后，合作导师；胡荣贵
主持或参加科研项目:
国家自然科学基金委员会, 面上项目, 91539107, 利用微流控芯片技术研究AcSDKP对血管损伤后的重塑作用与机制, 2016-01至2018-12, 75万元, 结题, 参与
国家自然科学基金委员会, 面上项目, 31371423, 肿瘤细胞中BIT1介导内质网应激诱导细胞凋亡的机制研究, 2014-01至2017-12, 75万元, 结题, 参与
国家自然科学基金委员会, 面上项目, 31301163, GABAB受体对不同G蛋白亚型的动态激活机制研究, 2014-01至2016-12, 25万元, 结题, 参与
一、代表性论著
期刊论文
(1) Yang, L#., Xia, Z#., Feng, J., Zhang, M., Miao, P., Nie, Y., Zhang, X., Hao, Z., and Hu, R. Retinoic Acid Supplementation Rescues the Social Deficits in Fmr1 Knockout Mice. Front Genet 2022 13: 928393
(2) Xia, Z#., Wu, S., Wei, X., Liao, Y., Yi, P., Liu, Y., Liu, J., and Liu, J. Hypoxic ER stress suppresses beta-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1alpha for cell survival. Journal of Biological Chemistry 2019 294: 13811-13821
(3) Wu, Y., Shan, B., Dai, J., Xia, Z., Cai, J., Chen, T., Lv, S., Feng, Y., Zheng, L., Wang, Y., Liu, J., Fang, J., Xie, D., Rui, L., Liu, J., and Liu, Y. Dual role for inositol-requiring enzyme 1alpha in promoting the development of hepatocellular carcinoma during diet-induced obesity in mice. Hepatology 2018 68: 533-546
(4) Shan, B., Wang, X., Wu, Y., Xu, C., Xia, Z., Dai, J., Shao, M., Zhao, F., He, S., Yang, L., Zhang, M., Nan, F., Li, J., Liu, J., Liu, J., Jia, W., Qiu, Y., Song, B., Han, J. J., Rui, L., Duan, S. Z., and Liu, Y. The metabolic ER stress sensor IRE1alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity. Nature Immunology 2017 18: 519-529
(5) Sun, B., Chen, L., Liu, L., Xia, Z., Pin, J. P., Nan, F., and Liu, J. A negative allosteric modulator modulates GABAB-receptor signalling through GB2 subunits. Biochemical Journal 2016 473: 779-787
(6) Duan, B., Zheng, X., Xia, Z., Fan, X., Guo, L., Liu, J., Wang, Y., Ye, Q., and Zhang, L. Highly biocompatible nanofibrous microspheres self-assembled from chitin in NaOH/urea aqueous solution as cell carriers. Angewandte Chemie. International Ed. In English 2015 54: 5152-5156
